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FR2
Mechanism of action The HGH fragment 176-191 (AOD9604) is a lipolytic peptide derived from the C-terminal segment of growth hormone. Preclinical studies indicate indirect action via β3-adrenergic receptors (β3-AR): the peptide increases β3-AR expression in adipocytes, contributing to restoration of lipolytic sensitivity. Unlike full HGH, this fragment does not appear to significantly affect insulin sensitivity, making it a distinct research subject for lipid metabolism. Research applications • Mobilization of lipid reserves and fat metabolism • Expression and regulation of β3-adrenergic receptors in adipocytes • Research models on obesity and fat storage Biological properties studied • Lipolytic effect without notable insulinotropic action • Potential to increase energy expenditure • Selectivity of action compared to native HGH • Purity: ≥99% (HPLC) • Presentation: Lyophilized powder • Storage: 2-8°C Research use only.
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